It is the time of the Spanish Inquisition. Maria does not like what is going on during the "Auto De Fe". When she speaks out, she is arrested and accused of being a witch. Torquemada has plans for her! He orders her tortured, and her tongue to be cut out. Her husband attempts to free her...

An anonymous, but deadly man rides into a town torn by war between two factions, the Baxters and the Rojo's. Instead of fleeing or dying, as most other would do, the man schemes to play the two sides off each other, getting rich in the bargain.

Jack Beauregard, once the greatest gunslinger of the Old West, only wants to move to Europe and retire in peace. But a young gunfighter, known only as "Nobody", idolizes him and wants to see him go out in a blaze of glory. He arranges for Jack to face the 150-man gang known as The Wild Bunch and earn his place in history.

Two bounty hunters are after the same man, Indio. At first, they go their own ways, but eventually get together to try and find him. But are they after him for the same reason ?

Blondie (The Good) is a professional gunslinger who is out trying to earn a few dollars. Angel Eyes (The Bad) is a hit man who always commits to a task and sees it through, as long as he is paid to do so. And Tuco (The Ugly) is a wanted outlaw trying to take care of his own hide. Tuco and Blondie share a partnership together making money off Tuco's bounty, but when Blondie unties the partnership, Tuco tries to hunt down Blondie. When Blondie and Tuco comes across a horse carriage loaded with dead bodies, they soon learn from the only survivor (Bill Carson) that he and a few other men have buried a stash of gold in a cemetery. Unfortunately Carson dies and Tuco only finds out the name of the cemetery, while Blondie finds out the name on the grave. Now the two must keep each other alive in order to find the gold. Angel Eyes (who had been looking for Bill Carson) discovers that Tuco and Blondie meet with Carson and knows they know the location of the gold...