Brandon is a 30-something man living in New York who is unable to manage his sex life. After his wayward younger sister moves into his apartment, Brandon's world spirals out of control. From director Steve McQueen (Hunger), Shame is a compelling and timely examination of the nature of need, how we live our lives and the experiences that shape us.

Mona Gray is a 20-year-old loner who, as a child, turned to math for salvation after her father became ill. As an adult, Mona now teaches the subject and must help her students through their own crises.

Ben Kalman is aging: he has heart problems, his marriage is over, he's lost a fortune after being caught cutting corners in his East Coast car business, and he's sleeping with as many women as possible - the younger the better. He's chosen his current girlfriend, Jordan, because her father can help him get a new auto dealership; she's asked him to escort her daughter, Allyson, 18, on a visit to a Boston college campus. He behaves badly, and there are consequences to his love life, his finances, and his relationship with his daughter and grandson. Is there anywhere he can turn?

In early afternoon, four armed men hijack a subway train in Manhattan. They stop on a slight incline, decoupling the first car to let the rest of the train coast back. Their leader is Ryder; he connects by phone with Walter Garber, the dispatcher watching that line. Garber is a supervisor temporarily demoted while being investigated for bribery. Ryder demands $10 million within an hour, or he'll start shooting hostages. He'll deal only with Garber. The mayor okays the payoff, the news of the hostage situation sends the stock market tumbling, and it's unclear what Ryder really wants or if Garber is part of the deal. Will hostages, kidnappers, and negotiators live through this?