On the eve of the 40th anniversary of the Gay Rights Movement, the film explores the drama, struggle and enduring legacy of the first-ever gay play and subsequent Hollywood movie to successfully reach a mainstream audience. Beloved by some for breaking new ground, and condemned by others for reinforcing gay stereotypes, The Boys in the Band sparked heated controversy that still exists four decades later.

Good-natured astronomer Sam is devastated when the love of his life, Linda, leaves him for a suave Frenchman named Anton. He therefore does what every other normal dumpee would do; go to New York and set up home in the abandoned building opposite his ex-girlfriend's apartment, intent on winning her back and waiting until she decides to leave her current lover. What Sam does not count on is being joined several weeks later by ultra hip tomboy Maggie, a photographer and motor-cyclist who is determined to get revenge on Anton, her ex-fiance. Hostile at first, the two of them eventually join forces in an attempt to separate the couple, and ruin Anton's life. However, complications ensue when Sam and Maggie start falling for each other.