When Jake LaMotta steps into a boxing ring and obliterates his opponent, he's a prizefighter. But when he treats his family and friends the same way, he's a ticking time bomb, ready to go off at any moment. Though LaMotta wants his family's love, something always seems to come between them. Perhaps it's his violent bouts of paranoia and jealousy. This kind of rage helped make him a champ, but in real life, he winds up in the ring alone.

Henry Hill is a small time gangster, who takes part in a robbery with Jimmy Conway and Tommy De Vito, two other gangsters who have set their sights a bit higher. His two partners kill off everyone else involved in the robbery, and slowly start to climb up through the hierarchy of the Mob. Henry, however, is badly affected by his partners success, but will he stoop low enough to bring about the downfall of Jimmy and Tommy?