In Moscow, five young people lead the charge against an alien race who have attacked Earth via our power supply.

Among normal humans live the "Others" possessing various supernatural powers. They are divided up into the forces of light and the forces of the dark, who signed a truce several centuries ago to end a devastating battle. Ever since, the forces of light govern the day while the night belongs to their dark opponents. In modern day Moscow the dark Others actually roam the night as vampires while a "Night Watch" of light forces, among them Anton, the movie's protagonist, try to control them and limit their outrage.

Max Peterson is a globe-trotting techno-whiz who installs security systems on computers. He receives an anonymous gift: a phone which sends messages that enable him to win at a casino. Max soon finds himself pursed by hit men, the casino's security chief, and a CIA operative. Who's sending Max messages? Previous recipients of similar windfalls have ended up dead. After a couple of close scrapes, Max realizes he's in danger, so he tries to find out the root of the conspiracy - which seems to have access to every security camera in the world - before he's the next victim. Why is this happening to him, and who can he trust?

Anton belongs to the Forces of the Light as well as his powerful girlfriend and apprentice, but his son is a powerful teenager from the Darkness and Anton protects him. When the balance between Light and Darkness is affected by the death of some evil vampires, Anton is framed and accused of the murders, and he chases an ancient chalk that has the power of changing the destiny of its owner.