At the age of forty Dame Margot Fonteyn is considered to be past her best as a prima ballerina and Ninette de Valois is reducing her roles at the Royal Ballet. Then the exciting young Russian dancer Rudolf Nureyev, a recent defector to the West, comes into her life and her bed and revitalizes her career. Frederick Aashton creates a new ballet for them and they become the golden couple of the ballet world. However, Margot is married to Roberto 'Tito' Arias, a Panamanian politician of dubious repute who is not sympathetic to her calling and is probably faithless. When he is shot and paralyzed for life Margot must carry on dancing well into her sixties in order to pay for his costly treatment though she still collaborates with Rudolf in the occasional ballet.

The cynical and skeptical writer Mike Enslin writes books evaluating supernatural phenomena in hotels, graveyards and other haunted places, usually debunking the mystery. While writing his last book, he travels from Los Angeles to New York to spend one night in the evil room 1408 of the Dolphin Hotel, which is permanently unavailable for guests. The reluctant manager Mr. Gerald Olin objects to his request and offers an upgrade, expensive booze and finally the reports relating the death of more than fifty guests along decades in the cursed room. However, Mike threatens Mr. Oiln, promising to sue the hotel, and finally checks in the room. Along the night, he finds that guests of room 1408 can check in when they like, but they can never leave the room alive.